Transport functions of riboflavin carriers in the rat small intestine and colon: site difference and effects of tricyclic-type drugs
S Tomei, H Yuasa, K Inoue, J Watanabe - Drug Delivery, 2001 - Taylor & Francis
S Tomei, H Yuasa, K Inoue, J Watanabe
Drug Delivery, 2001•Taylor & FrancisThe present study was aimed at kinetically characterizing the newly found carrier-mediated
riboflavin transport system in the rat colon, comparing it with that in the small intestine, and
also probing the potential roles of these transport systems in intestinal drug absorption.
Riboflavin transport, evaluated by measuring the initial uptake into everted intestinal tissue
sacs, was saturable with a Michaelis constant (Km
riboflavin transport system in the rat colon, comparing it with that in the small intestine, and
also probing the potential roles of these transport systems in intestinal drug absorption.
Riboflavin transport, evaluated by measuring the initial uptake into everted intestinal tissue
sacs, was saturable with a Michaelis constant (Km
The present study was aimed at kinetically characterizing the newly found carrier-mediated riboflavin transport system in the rat colon, comparing it with that in the small intestine, and also probing the potential roles of these transport systems in intestinal drug absorption. Riboflavin transport, evaluated by measuring the initial uptake into everted intestinal tissue sacs, was saturable with a Michaelis constant (Km
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